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BPC-157 was first isolated from gastric juice, and it is thought to help protect and heal the stomach on an ongoing basis

It is contraindicated for use in neonates and premature infants due to the risk of serious adverse reactions, including gasping syndrome

In regards to its effect on mitochondria, clinical studies have shown that it can stimulate mitochondrial biogenesis, leading to an increase in the number and function of mitochondria within cells (Yue et al., 2022)

The fatigue during early semaglutide use more likely results from caloric restriction, changes in eating patterns, and the medication adjusting appetite and satiety signals

Each works on a different lever, which is exactly why a provider may use one, another, or a combination depending on your goals